Hazard statements

What are H-statements and why are they important?

H-statements are standardised phrases that accurately describe risks associated with chemical substances and mixtures. They are not general labels, but precise descriptions of hazards – for example whether a product causes eye irritation, is flammable, or poses a danger to the environment.

H-statements are an integral part of the European CLP system (Classification, Labelling and Packaging), i.e. the classification, labelling and packaging of chemical substances and mixtures, which is mandatory throughout the EU under Regulation (EC) No 1272/2008. This system is based on the international framework GHS (Globally Harmonised System), created by the United Nations (UN), which harmonises the labelling of chemicals across countries and continents.

Main functions of H-statements

H-statements fulfil several important functions:

  • Health protection – Inform workers, consumers and emergency services about the risks posed by a product – e.g. “H314 – Causes severe skin burns and eye damage.

  • Standardization – Thanks to standardised numbering, H-statements have a clear and consistent meaning that is preserved across all EU languages – making translation, control and understanding easier across languages and countries.

  • Legal enforceability – Their inclusion on labels and in safety data sheets is mandatory and legally enforceable. Incorrect use (e.g. paraphrasing or incorrect translation) may have legal consequences.

How are H-statements divided?

Category
Hazard type
Example
H2xx
Physical hazard
Highly flammable liquid and vapour.
H3xx
Human health
Harmful if swallowed.
H4xx
Environment
Very toxic to aquatic life.

Use of H-statements in practice

In the safety data sheet (SDS)

H-statements play a key role in informing users about specific hazards. They appear primarily in Section 2.2 of the safety data sheet, where they are displayed together with:

  • Precautions (safe handling instructions),
  • the signal word (“Danger” or “Warning”). Their wording must correspond to the official text set out in Annex III to the CLP Regulation.

It is not permitted to:

  • create your own translations,
  • modify the wording,
  • paraphrase.

For example, H319 is always worded in English as: “Causes serious eye irritation.”

It cannot be rewritten, for example, as “May irritate the eyes.” – such wording does not comply with legal requirements and may result in invalid labelling or penalties.

On the label

The label is often the only document available to the user. It must therefore contain all the information necessary for safe handling while also complying with the legal requirements of the CLP Regulation.

H-statements on the label must be:

  • readable and clearly visible (appropriate font size and contrast),
  • provided in accordance with the classification of the entire mixture or substance,
  • provided in their full wording, without abbreviations.

The order of individual H-statements and Precautions on the label is not strictly prescribed – the supplier may choose it at their own discretion. However, it is important that:

  • the statements are grouped by language – English must not be mixed with other languages within the same section,
  • the statements are reproduced exactly as specified by CLP, without abbreviations or modifications – multilingual labels should be clearly structured and all language versions should be complete.

The label must also contain:

  • Hazard pictograms (e.g. flame, skull and crossbones, exclamation mark),
  • the signal word (“Danger” or “Warning”),
  • Precautions – safe handling instructions, e.g. “Wear protective eyewear”.

New EUH-statements among standard hazard statements

As part of the revision of the CLP Regulation, new statements designated as EUH have been introduced, expanding the existing labelling system to cover additional specific hazards that the GHS does not yet address. Unlike previous informational supplements, these new EUH statements have the status of standard H-statements.

EUH – Overview of the new standard EUH-statements:

Category
Hazard type
EUH380
May cause endocrine disruption in humans.
EUH381
Suspected of causing endocrine disruption in humans.
EUH430
May cause endocrine disruption in the environment.
EUH431
Suspected of causing endocrine disruption in the environment.
EUH440
Accumulates in the environment and living organisms including in humans.
EUH441
Strongly accumulates in the environment and living organisms including in humans.
EUH450
Can cause long-lasting and diffuse contamination of water resources.
EUH451
Can cause very long-lasting and diffuse contamination of water resources.

Like H-statements, these new EUH-statements must be included on labels and in safety data sheets if the product meets the criteria for the relevant classification. Their introduction represents a further step by the EU beyond GHS and reflects current scientific knowledge – particularly in the area of endocrine disruptors and environmental protection.

List of H-statements

H2xx – Physical hazard

Codes
Version
H200
Unstable explosives.
H201
Explosive; mass explosion hazard.
H202
Explosive, severe projection hazard.
H203
Explosive; fire, blast or projection hazard.
H204
Fire or projection hazard.
H205
May mass explode in fire.
H206
Fire, blast or projection hazard; increased risk of explosion if desensitising agent is reduced.
H207
Fire or projection hazard; increased risk of explosion if desensitising agent is reduced.
H208
Fire hazard; increased risk of explosion if desensitising agent is reduced.
H220
Extremely flammable gas.
H221
Flammable gas.
H222
Extremely flammable aerosol.
H223
Flammable aerosol.
H224
Extremely flammable liquid and vapour.
H225
Highly flammable liquid and vapour.
H226
Flammable liquid and vapour.
H228
Flammable solid.
H229
Pressurised container: May burst if heated.
H230
May react explosively even in the absence of air.
H231
May react explosively even in the absence of air at elevated pressure and/or temperature.
H232
May ignite spontaneously if exposed to air.
H240
Heating may cause an explosion.
H241
Heating may cause a fire or explosion.
H242
Heating may cause a fire.
H250
Catches fire spontaneously if exposed to air.
H251
Self-heating: may catch fire.
H252
Self-heating in large quantities; may catch fire.
H260
In contact with water releases flammable gases which may ignite spontaneously.
H261
In contact with water releases flammable gases.
H270
May cause or intensify fire; oxidiser.
H271
May cause fire or explosion; strong oxidiser.
H272
May intensify fire; oxidiser.
H280
Contains gas under pressure; may explode if heated.
H281
Contains refrigerated gas; may cause cryogenic burns or injury.
H290
May be corrosive to metals.

H3xx – Human health

Codes
Version
H300
Fatal if swallowed.
H301
Toxic if swallowed.
H302
Harmful if swallowed.
H310
Fatal in contact with skin.
H311
Toxic in contact with skin.
H312
Harmful in contact with skin.
H330
Fatal if inhaled.
H331
Toxic if inhaled.
H332
Harmful if inhaled.
H304
May be fatal if swallowed and enters airways.
H314
Causes severe skin burns and eye damage.
H315
Causes skin irritation.
H317
May cause an allergic skin reaction.
H318
Causes serious eye damage.
H319
Causes serious eye irritation.
H334
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H335
May cause respiratory irritation.
H336
May cause drowsiness or dizziness.
H340
May cause genetic defects.
H341
Suspected of causing genetic defects.
H350
May cause cancer.
H350i
May cause cancer by inhalation.
H351
Suspected of causing cancer.
H360
May damage fertility or the unborn child.
H360D
May damage the unborn child.
H360Df
May damage the unborn child. Suspected of damaging fertility.
H360F
May damage fertility.
H360FD
May damage fertility. May damage the unborn child.
H360Fd
May damage fertility. Suspected of damaging the unborn child.
H361
Suspected of damaging fertility or the unborn child.
H361d
Suspected of damaging the unborn child.
H361f
Suspected of damaging fertility.
H361fd
Suspected of damaging fertility. Suspected of damaging the unborn child.
H362
May cause harm to breast-fed children.
H370
Causes damage to organs.
H371
May cause damage to organs.
H372
Causes damage to organs through prolonged or repeated exposure.
H373
May cause damage to organs through prolonged or repeated exposure.

H4xx – Environment

Codes
Version
H400
Very toxic to aquatic life.
H410
Very toxic to aquatic life with long lasting effects.
H411
Toxic to aquatic life with long lasting effects.
H412
Harmful to aquatic life with long lasting effects.
H413
May cause long lasting harmful effects to aquatic life.
H420
Harms public health and the environment by destroying ozone in the upper atmosphere.

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